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Scientific Track
 
 
[Nov.2007-To date] Postdoc in the Institite of Ecological Chemistry in Helmholtz Research Center Munich - 12Tesla FT-ICR-MS laboratory.
 
  Organic Mass Spectrometry with emphasis of pesticides and herbicides environmental and catalytic biodegradation.
 
  Elucidation of advanced fragmentation mechanisms of ionic systems as well as ion-neutral recombination mechanisms by quantum mechanical DFT investigations and mass spectrometric collision induced dissociation experiments.
 
  Transition state engineering for several gas phase rearrangements of ionic and neutral systems and study of isodesmic reactions. Calculations of electronic properties of molecular structures.
 
[Dec.2005- Nov.2007] Postdoc in Max-Planck Institute for atmospheric chemistry:
 
  “Mass spectrometric investigations of organic aerosols using different external ionisation sources in Triple-Quadrupole-TOF LC-MS/MS hybrid system”.
 
 “Elucidation of gas phase fragmentation mechanisms for closed shell anions of different oxocarboxylic acids by use of collision induced dissociation experiments and DFT quantum mechanical calculations”.
 
[2004- Dec.2005] Scholarship holder of VCI (Verband der Chemischen Industrie) & PhD. in gas phase chemistry ICR mass spectrometry in the University of Bremen/Germany under the supervision of Prof. Dr. Karl-Peter Wanczek.
 
“Gas Phase Negative Ion Chemistry of Tris(trifluoromethyl)phosphine and Characterization of Cylindrical Open ICR cell with electrodes of different diameters”.
 
[End of 2003] Diplom Degree in Chemistry (Total Grade = 1) in the University of Bremen.
 
[2001-2005] Seminar and Lab Tutor for the course “Chemistry for Physicists” in the University of Bremen.
 
[2003-2005] Seminar and Lab Tutor for the course “Micro qualitative Analysis for Chemists” in the University of Bremen.
 
[2000-2001] German Studies with DSH certificates from the University of Freiburg and the University of Bremen.
 
[1997-1999] Computer Teacher in Bayan Co. Computer Institute for the course: “Advanced Excel and Access Programming” in Damascus.
 
[1992-1996] Bachelor Degree of Science (Total grade : Very good) from the University of Damascus.

 

Computer Skills

• Visual Basic for Excel Programming. Computer Skills:

 • MATLAB (Advanced Math Program). I designed new programs for laboratorial system control and automation - coupling of mass spectrometer with auto samplers by the use of microcontrollers.

• Gaussian for quantum mechanical calculations of chemical structures (energy barrier heights for isodesmic chemical reactions, electron affinities, proton affinities, optimized geometries, NMR chemical shifts, NCIS magnetic shields).

 • SIMION for ion trajectory calculations for design inventions. Simulation of ions under combined electrical and magnetic fields. I discovered new types of ion motion in novel electrical devices. • Autodesk Inventor (Advanced 3D CAD program for construction of metal works).

• Hierarcial Clustering Explorer for data classification and biomarker identification. • Programs for controling several mass spectrometers and performing data analysis (Bruker‘s Data Analysis, MDS Sciex Analyst, Bruker‘s Xmass, Bruker‘s Aspect & Quantra software).

 
Instruments:
 
Bruker’s research grade FT-ICR mass spectrometer with 7T Oxford Magnet.
 
 
Brucker’s APEX FT-ICR mass spectrometer with 12T Magnex magnet.
 
QSTAR Triple Quadrupole- Orthogonal acceleration - TOF-MS/MS hybrid system from MDS Sciex.
 
Quantra FT-ICR mass spectrometer for GC-MS analysis.
 
 
Memberships:
 
 
 
Peer reviewed publications:

1. Gas Phase FT ICR Investigation of the Production of Phosphoranides and Ion Chemistry of Tris(trifluoromethyl)phosphine.
B Kanawati, KP Wanczek. International Journal of Mass Spectrometry, (2007): 264/(2-3), 164-174.

2. Characterisation of a New Open Cylindrical ICR Cell with unusual geometry.
B Kanawati, KP Wanczek. Review of Scientific Instruments, (2007): 78 (7), 074102.

3. Mass spectrometric characterisation of small oxocarboxylic acids and gas phase ion fragmentation mechanisms studied by Electrospray Triple Quadrupole-MS/MS-TOF system and DFT Theory.
B Kanawati, S Joniec, R Winterhalter, GK Moortgat. International Journal of Mass Spectrometry, (2007): 266 (1-3) 97-113.

4. Characterisation of a New Open Cylindrical ICR Cell for Ion-Ion Collision Studies.
B Kanawati, KP Wanczek. International Journal of Mass Spectrometry, (2008): 269, (1-2), 12-23.

5. Mass spectrometric characterisation of beta-caryophyllene ozonolysis products in the aerosol studied by Electrospray Triple Quadrupole-MS/MS-TOF system and DFT Theory.
B Kanawati, F Herrmann, S Joniec, R Winterhalter , GK Moortgat. Rapid Communications in Mass Spectrometry. (2008): 22 (2), 165-186.

6. Oligomer formation during gas-phase ozonolysis of small alkenes and enol ethers: new evidence for the central role of the Criegee Intermediate as oligomer chain unit.
A Sadezky, R Winterhalter, B Kanawati, A Römpp, B Spengler, A Mellouki, G Le Bras, P Chaimbault, GK Moortgat. Atmospheric Chemistry and Physics Discussions (2007): 7, 14041–14102.

7. RF-driven Ion-Ion Long Range Interaction in a New Open Cylindrical ICR cell.
B Kanawati, KP Wanczek. International Journal of Mass Spectrometry (2008): 274, (1-3), 30-47.

8. Mass spectrometric characterisation of 4-oxopentanoic acid and gas phase ion fragmentation mechanisms studied by Electrospray Triple Quadrupole-MS/MSTOF system and DFT Theory.
B Kanawati, S Joniec, R Winterhalter , GK Moortgat, Rapid Communications in Mass Spectrometry, (2008): 22 (14), 2269-2279.


9. Photocatalytic Reactions of Imazamox at TiO2, H2O2 and TiO2/H2O2 in Water Interfaces: Kinetic and Photoproducts Study.
M Harir, A Gaspar, B Kanawati, M Frommberger, A Fekete, D Martens, A Kettrup, M El Azzouzi, P Schmitt-Kopplin J. Appl. Cat. B, (2008): 84 (3-4), 524-532.

10. Exploring Rearrangements along the Fragmentation Pathways of Diuron Anion: A combined experimental and computational investigation
B Kanawati, M Harir, P Schmitt-Kopplin International Journal of Mass Spectrometry, (2009): 288 (1-3), 6-15.

11. Automated microextraction sample preparation coupled on-line to FT-ICR-MS: application to desalting and concentration of river and marine dissolved organic matter.
G Morales-Cid. , I Gebefügi, B Kanawati, M Harir, P Schmitt-Kopplin, M Valcarcel, BM Simonet, S Cardenas. Analytical Bioanalytical Chemistry, (2009): 395:797–807.

12. The gas-phase ozonolysis of ß-caryophyllene (C15H24). Part I: an experimental study.
R Winterhalter, F Herrmann, B Kanawati, TL Nguyen, J Peeters, L Vereeckenb, GK Moortgatat. Physical Chemistry Chemical Physics (2009): 11, 4152–4172.

13. The gas-phase ozonolysis of -caryophyllene (C15H24). Part II: A theoretical Study.
TL Nguyen, R Winterhalter, GK Moortgat, B Kanawati, J Peeters, L Vereecken. Physical Chemistry Chemical Physics (2009): 11, 4173 – 4183.

14. Can tetra-tert-butylethylene be formed by ion–ion recombination or ion–molecule reaction of two di-tert-butylcarbene units?—a DFT study
B Kanawati, D Lenoir, P Schmitt-Kopplin. Journal of Physical Organic Chemistry. Journal of Physical Organic Chemistry. (2010): 24, 83–91.

15. High molecular diversity of extraterrestrial organic matter in Murchison meteorite revealed 40 years after its fall.
P Schmitt-Kopplin , Z Gabelica, R Gougeon, A Fekete, B Kanawati, I Gebefuegi, G Eckel, N Hertkorn.Proceedings of the National Academy of Sciences, (2010): 107 (7), 2763-2768.

16. Exploring rearrangements along the fragmentation of glutaric acid negative ion:A combined experimental and theoretical study.
B Kanawati, P Schmitt-Kopplin. Rapid Communications in Mass Spectrometry (2010): 24 (8), 1198 – 1206.


17. Pathway analysis of the transcriptome and metabolome of a salt sensitive and tolerant poplar species reveals evolutionary adaption of stress tolerance mechanisms.
D Janz, K Behnke, JP Schnitzler, B Kanawati, P Schmitt-Kopplin, A Polle (2010): BMC Plant Biology, 10, 150.

18. Hydrolysis of Mefenpyrdiethyl: an analytical and DFT investigation
A Chnirheb, M Harir, B Kanawati, A Fekete, M El Azzouzi, N Hertkorn, P Schmitt-Kopplin Analytical and Bioanalytical Chemistry (2010): 398(5), 2325-34.

19. Mass spectrometric steriochemical differentiation between alpha and beta ascorbic acid 2-glycosides: Experimental and DFT study.
B Kanawati, VV Saint-Paul, AR Schaefner, P Schmitt-Kopplin. Rapid Communications in Mass Spectrometry, (2011): 25(6):806-14.

20. The Arabidopsis glucosyltransferase UGT76B1 conjugates isoleucic acid and modulates plant defense and senescence
VV Saint Paul, B Kanawati, W Zhang, B Geist, T Faus-Keßler, P Schmitt-Kopplin, AR Schäffner (2011): Plant Cells. In press.

21. Novel Cysteine Tags for the Sequencing of Non-Tryptic Disulfide Peptides of Anurans:
ESI-MS Study of Fragmentation Efficiency
TY Samgina, EA Vorontsov, VA Gorshkov, KA Artemenko, IE Nifant’ev, B Kanawati,P Schmitt-Kopplin, RA Zubarev, AT Lebedev. American Society for Mass Spectrometry, (2011), DOI: 10.1007/s13361-011-0247-0.

22. Detection of Peptidic Sequences in the Ancient Acidic Sediments of Río Tinto, Spain.
M Colín-García & B Kanawati , M Harir , P Schmitt-Kopplin , R Amils , V Parro , M García , D Fernández-Remolar. Origins of Life and Evolution of Biospheres, DOI 10.1007/s11084-011-9258-x.

23. Photocatalytic Efficiency of TiO2 P-25 and Humbikat UV100 against Mefenpyrdiethyl in Water: Kinetics and Degradation Products Study
Amina Chnirheb, Mourad Harir, Basem Kanawati, Mohammed El Azzouzi, Istvan Gebefügi, Philippe Schmitt-Kopplin. Journal of Environmental Science (2011).

24. Dissolved organic matter in sea spray: a transfer study from marine surface water to aerosols.
Philippe Schmitt-Kopplin, Gérard Liger-Belair, Boris P. Koch, Ruth Flerus, Gerhard Kattner, Mourad Harir, Basem Kanawati, Marianna Lucio, Dimitrios Tziotis, Norbert Hertkorn, Istvan Gebefügi. Biogeosciences Discussions. A journal of the European Geosciences Union (2011). 8, 11767–11793.

25. Analysis of glutathione-S-transferases from Arabidopsis in yeast.
Matthias P. Krajewski, Basem Kanawati, Agnes Fekete, Nathalie Kowalski, Phillippe Schmitt-Kopplin, and Erwin Grill. Journal of Photochemistry (2012), http://dx.doi.org/10.1016/j.phytochem.2012.04.016.

26. Attachment of Chloride Anion to Sugars: Mechanistic Investigation and Discovery of a New Dopant for Efficient Sugar Ionization/Detection in Mass Spectrometers
Lemia Boutegrabet, Basem Kanawati, Istvan Gebefügi, Dominique Peyron, Philippe Cayot, Régis D. Gougeon, Philippe Schmitt-Kopplin. Chemistry, A European Journal (2012), 18(41), 13059–13067.

27.Bis-dibenzo[a.i]fluorenylidene, does it exist as a stable 1,2-diradical?
Basem Kanawati, Alexander Genest, Philippe Schmitt-Kopplin, Dieter Lenoir. Journal of Molecular Modeling (2012). DOI: 10.1007/s00894-012-1502-4.

28. Pre-focusing inside a linear ion beam guide - SIMION study.
Basem Kanawati, Karl-Peter Wanczek, Istvan Gebefügi, Philippe Schmitt-Kopplin. International Journal of Mass Spectrometry, Special Issue (2012), 325, 25–29.

29.Atmospheric CO2 determines metabolic differences between isoprene and non-isoprene emitting poplas – low CO2 as a selective trait for the evolution of plant isoprene emission.
Danielle A. Way, Andrea Ghirado, Basem Kanawati, Jürgen Esperschütz, Russel K. Munson, Robert B. Jackson, Philippe Schmitt-kopplin, Jörg-Peter Schnitzler. Submitted to Proceedings of the National Academy of Sciences (PNAS), (2012).

30. Exploring fragmentation pathways of mefenpyrethyl anion in the gas phase using high resolution mass spectrometry: New transformation of phenylpyrazole to an indol derivative.
Mourad Harir, Basem Kanawati, Philippe Schmitt-Kopplin. Submitted to European journal of Mass Spectrometry (2012).

31. Two contrasting poplar species show different isoprene emission rates and photosynthetic capacities under combined high salinity and sunflecks
Katja Behnke, Andrea Ghirardo, Jürgen Esperschütz, Basem Kanawati, Dennis Janz, Ulö Ninemets, Andrea Polle, Jörg-Peter Schnitzler, Maaria Rosenkranz. Submitted to the Journal of Tree Physiology (2012).

32.Manganese speciation in paired serum and CSF samples using SEC- DRC-ICP-MS and CE-DRC-ICP-MS
B. Michalke, M. Lucio, B. Kanawati, A. Berthele. In press, Analytical Bioanalytical Chemistry Journal (2013).

33. Review on liquid chromatography mass spectrometry techniques in non-targeted metabolomics research: historical aspects and perspectives. Special issue: state-of-the art of (UHP)LC-MS techniques and their practical application
Sara Forcisi, Franco Moritz, Basem Kanawati, Dimitrios Tziotis, Philippe Schmitt-Kopplin. In press, Journal of Chromatography A (2012).

34. Phosphoranide production and decomposition in the gas phase.
Basem Kanawati, Karl-Peter Wanczek. Submitted to International Journal of Mass Spectrometry (2013).

 

 

 

Talks:

 
  1. Fourier Transform ion cyclotron resonance mass spectrometry and computational tools in modern analytical chemistry. Moscow State University – Russia (2011).

 

  1. Fourier Transform ion cyclotron resonance mass spectrometry and computational tools in modern analytical chemistry. Russian Academy of Science – Russia (2011).

 

  1. Organic ion rearrangements and elucidation of new fragmentation mechanisms in the gas phase -  DFT Studies. Chemiedozententagung (2010) – Gießen, Germany.

 

  1. Modern mass spectrometers and their chemical applications. University of Damascus – Faculty of Sciences, Damascus, Syria (2010).

 

  1. Advanced analytical techniques in chemistry. Faculty of Pharmacy, Arab International University, Damascus, Syria (2010).

 

  1. Ion rearrangements of Di-tert-butylcarbene and investigation of ion-ion and ion-molecule reactions as new routes for synthesis of Tetra-tert-butylethylene -  A DFT Study, (2009), Chemiedozententagung, Göttingen.

 

  1. Mass spectrometric characterization of environment-related organic ions by
    internal energy deposition implemented in a quadrupole / 12T FT-ICR Hybrid
    system and studied by DFT quantum mechanical theory. Bruker Seminar Tour –
    Köln (2008).

 

  1. Elucidation of new fragmentation mechanisms for the negative ions of small oxocarboxylic acids by the use of dft theory and triplequad-tof mass spectrometer coupled to electrospray ionization source. Chemiedozententagung (2008) / TU-Kaiserslautern.

 

  1. Mass spectrometric characterization of environment-related organic ions by

internal energy deposition implemented in a quadrupole / 12T FT-ICR Hybrid

system and studied by DFT quantum mechanical theory. Bruker Seminar Tour –

Munich (2008).

 

  1. SIMION simulations of ion trajectories in a novel quadrupole mass filter / icr cell with an unusual geometry. DPG (2008) TU-Darmstadt.

 

  1. Instrumental developments in FT-ICR-MS and CID-DFT methods for structural elucidation of multi-functional organic compounds combined with advanced gas phase mechanistic studies. (2007) Hahn-Meitner-Institute - Berlin.

 

  1. SIMION simulations of ions inside a new ICR-cell geometry. (2007) School of Engineering  University of Duisburg-Essen.

 

  1. CID-DFT methods for structural elucidations of new multi-functional organic compounds formed due to sesquiterpene analysis by the use of a Quistor. (2007) Clinical Center of Göttingen University.

 

  1. Mass spectrometric characterization of the organic oxidation products in the aerosol formed by ß-Caryophyllene gas phase ozonolysis. Katholische Universität Leuven - Belgien (2007).

 

 

  1. Gas phase mechanistic studies for the fragmentation of negative parent ions of oxocarboxylic acids by the use of TripleQuad-TOF-MS and ion chemistry of phosphoranides, studied by a new FT-ICR-cell and CID-DFT methods. Universität Karlsruhe (2007).

 

  1. Instrumental developments in FT-ICR-MS and CID-DFT methods for structural elucidation of multifunctional compounds combined with advanced gas phase mechanistic studies. GSF Forschungszentrum  Neuherberg bei München (2007).

 

  1. structural elucidation of isomers of beta-caryophyllene oxidation products by use of CID (Collision Induced Dissociation) and DFT (Density Functional Theory). Max-Planck-Institute of Chemistry - Mainz (2007).

 

  1. Ion Cyclotron Resonanz Mass Spectrometry - Instrumental development and applications. FT-ICR special workgroup meeting (2007) - Konstanz.

 

  1. Mass spectrometric characterisation of small oxocarboxylic acids and gas phase ion fragmentation mechanisms studied by Electrospray Triple Quadrupole-MS/MS-TOF system and DFT Theory. DGMS (2007) - Bremen.

 

  1. Ion Cyclotron Resonanz Mass Spectrometry  Radial excitation patterns in a new ICR cell with unusual geometry. Max-Planck-Institute of Chemistry - Mainz (2006).

 

  1. Phosphoranides analysis in FT-ICR-MS with a five sections open cylindrical ICR cell. Freie Universität Berlin (2006).

 

  1. Ion-Ion collision experiments in multi-sections ICR cell with new geometry. Deutsche Physikalische Tagung (2006) - Frankfurt.

 

  1. Charcterization of a new cylindrical open ICR cell with electrodes of different diameters.  Verband der deutschen Industrie-Meeting (2006) - Münster.
 
 
 
Languages:
 
German, English, Arabic (Excellent)
French (beginner)
Year of Birth: 1974
 
Address:
 
Dr. Basem Kanawati
Helmholtz Center Munich
Institute of Ecological Chemistry
Ingolstädter Landstr. 1
85764 Neuherberg
Tel: +49-(0)89-3187-2412
Email: Kanawati.B@gmail.com